My husband has a rare genetic mutation that causes his fingernails to grow inverted

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Written by NewzyOfficial


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  1. He inherited this trait from his mother, and she inherited it from her father. For decades they thought it was just a quirk of their family tree, but recently our newborn daughter screened positive for a primary immunodeficiency. Changes to the FOXN1 gene cause this along with low T cells and other problems with the thymus. Children grow out of the immunodeficient side by age 2, but the nails stay like this for life.

    They’re called “spoon nails.”

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